lymphoid hyperplasia

Sheep (ovine) pulmonary adenocarcinoma (SPA)، also known as ovine pulmonary adneomatosis (OPA)، jaagsiekte and ovine pulmonary carcinoma (OPC) is a contagious lung tumor in sheep and، more rarely، in goats. This study was carried out in Khuzestan، in the southwest of Iran for a period of six months. A total number of 3985 native breed goats were clinically inspected and postmortem examination was recorded at the abattoir in Ahvaz. In necropsy 4 of these goats showed gross pulmonary lesions characteristic of classical pulmonary adenomatosis. The lungs were usually heavy and appeared “waterlogged”، but affected areas of the lungs were solid and light grey in color، and tissue looked slightly translucent. The cut surface showed numerous small، slightly-elevated white-grey nodules in each section. The affected alveoli in these areas were lined by proliferating cuboidal cells forming irregular folds and papillary projections. The bronchi and the bronchioles exhibited moderate epithelial hyperplasia and metaplasia. The bronchial associated lymphoid tissue and the smooth muscles of terminal and respiratory bronchioles were hyperplastic. The affected areas were essentially the same and also nearly similar to previous reports.