Prevalence of Primary Resistance to First Line Anti Tuberculosis Drugs and its Relation with Conversion of Smear Positive Pulmonary Tuberculosis
Author(s):
Abstract:
Background And Objectives
Emergence of drug resistant tuberculosis is a global concern. It might cause reduction in the rate of smear conversion in pulmonary tuberculosis. The aim of the present study was to examine the role of primary first line anti tuberculosis drugs resistance on the rate of sputum conversion. Materials And Methods
In a cohort study between 2005 and 2006، all smear positive pulmonary tuberculosis patients (90 cases) treated in Tabriz Tuberculosis and Lung Disease Research Center were included. Sputum smear and culture taken before and then 15 days and monthly for 6 months after standard four drug (INH، RIF، PZN، ETM) treatment were assessed. Results
There were 90 smear positive patients (47 males and 43 females) in the study period. The mean time was 1. 5 and 1 month for smear and culture negativity، respectively. Only one case was resistant to INH، RIF، and STM، for whom second line drugs were started. Other four resistant cases had positive smear until six months of treatment but their cultures were negative at the end of second month. At the seventh month، their smears were also negative. Conclusion
Drug resistant tuberculosis is very infrequent in Tabriz and this mandates prompt surveillance and treatment of the patients in order to prevent emergence of drug resistant tuberculosis.Keywords:
Language:
Persian
Published:
Medical Journal of Tabriz University of Medical Science, Volume:34 Issue: 3, 2012
Page:
96
magiran.com/p1038834
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
دسترسی سراسری کاربران دانشگاه پیام نور!
اعضای هیئت علمی و دانشجویان دانشگاه پیام نور در سراسر کشور، در صورت ثبت نام با ایمیل دانشگاهی، تا پایان فروردین ماه 1403 به مقالات سایت دسترسی خواهند داشت!
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!