The Antioxidant Effect of Vitamin C on Decreasing the Induced Chromosomal Damages by Low-Frequency Electromagnetic Field on Bone Marrow Erythrocytes of Male Balb/C Mouse

In the present study, the antioxidant effect of vitamin C on decreasing the induced chromosomal damages by low-frequency electromagnetic field on bone marrow erythrocytes of male Balb/C mouse has been investigated. In this experimental study, 48 adult male mouse (Balb/C) were randomly divided into four equal groups: control, test 1, test 2 and test 3. Control group were kept in normal conditions and the mice in test1 and test3 groups were intraperitoneally injected with 50 mg / kg of vitamin C for 8 consecutive days. Then the mice of test 3 and test 2 groups after the fifth day were exposed to electromagnetic waves with frequency of 50 Hz and intensity of 50 Gauss for 4 days and 4 hours per day. The mice in all different groups were sacrificed and micronucleus test were performed on the bone marrow polychromatic erythrocytes. The data were analyzed using spss software and ANOVA test at level p < 0.05. The frequency of micronucleus in bone marrow polychromatic erythrocytes of test3 group (3.107± 0.276) in comparison with test 2 group (9.29 ± 0.881) showed a significant reduction (p < 0.001). Vitamin C caused significant decrease in induced chromosomal damages by low-frequency electromagnetic waves in bone marrow polychromatic erythrocytes of adult male Balb/C mouse.