Effect of 10-day CoenzymeQ10 Supplementation on Blood lactate Concentration and Physical Performance in Young Trained Women

Lactic acid is the final product of anaerobic glycolysis, which is converted immediately into lactate. Most of the uptaken lactate is used as an aerobic substrate in skeletal muscle. Coenzyme Q10 is an essential electron carrier of the mitochondrial respiratory chain with antioxidant properties. It has been suggested that an intra-cellular shuttle is playing an important role in transferring lactate through mitochondrial membrane. Decreasing blood lactate concentration and its subsequent problems after a physical activity are of an important goals in physical performance. The Participants were 23 healthy young 20-30 years-old aerobic-trained women. They consumed 300mg/day of Coenzyme Q10 for 10 days. Blood lactate concentration and physical performance were measured at the beginning and at the end of the period using lactometer and Bruce test, respectively.At the beginning of the 10-day period blood, lactate concentration was 13.56±0.75 mmol/L, which was decreased to 11.12±0.67 mmol/L at the end of this period, significantly.Running time to exhaustion increased by 48.74±7.23 seconds significantly.Also VO2max increased by 3 Lit/min significantly. The results showed that the intake of 300 mg Coenzyme Q10 supplement in a 10-day period decreased blood lactate concentration and increased physical performance in the young trained women significantly.