The correlation between Glycosylated Hemoglobin and menstrual cycle length in Type 1 diabetic adolescents

Type 1 diabetes mellitus (T1DM) is the most common endocrine problem seen in children and adolescents; it is one of the main diseases which damages the body organs such as disrupt hypothalamic pituitary-gonadal function if blood sugar is not well controlled. This study aimed to find the correlation between Glycosylated Hemoglobin and menstrual cycle length in Type 1 diabetic adolescent referred to Iran Diabetes Association. This is a prospective longitudinal study. The subjects consisted of 60 diabetic girls aged 11-19 years selected by easy sampling method. The research instruments included a questionnaire, HbA1c sample laboratory test, interviews on the biophysical data. Data were analyzed through descriptive and inferential statistical tests. Our results showed that 86.6% of the patients had normal menstrual cycle.10% had oligomenorrhea and 3.33% amenorrhea. No one had primary amenorrhea. There was no statistically significant correlation between the mean HbA1c and menstrual cycle length. In this study, blood sugar rate and HbA1c in adolescents showed no significant effect on the menstrual cycle.