Central Giant cell Granuloma: (A Case Report)

Central giant cell granuloma formerly called «giant cell reparative granuloma،» is a non-neoplastic lesion. Some lesions demonstrate aggressive behaviors similar to that of a neoplasm. The mandibular / maxillary ratio has been reported as being from 2:1 to 3:1. Lesions are more common in the anterior portions of the jaws An 11-year old girl was referred with a chief complaint of chin expansion without pain. The radiographic exam ination showed a multilocular radiolucent lesion extended to lower border of the mandible. The histopathological examination showed a highly vascularized fibrous stroma with several multinucleated giant cells. Because of size of lesion، surgical approach was preferred. Most giant cell granulomas of the jaws are asymptomatic and usually first come to attention during a routine radiographic examination or as a result of painless expansion of the affected bone. So early diagnosis is very important in the prognosis.