Antibacterial activity of aqueous extracts of Mazuj and Ghalghaf galls of Quercus infectoria in Lorestan forests

Nowadays، bacterial infections and antibiotic resistance of their etiologic agents are among the most important challenges facing the health systems. Therefore the application of antimicrobial agents with natural origin has been deeply studied recently. The aim of this study is to evaluate antibacterial effects of aqueous extracts of Ghalghaf and Mazuj galls on gram-negative bacteria. The antibacterial activity of aqueous extract of two galls on the bacterial strains from clinical samples with multi-drug resistance (Pseudomonas aeruginosa، Acinetobacter baumannii، Escherichia coli) and reference bacterial strains were determined using agar dilution and agar diffusion methods. The aqueous extracts of both galls showed antibacterial activity against all studied bacterial strains. Inhibition zone diameter for aqueous extracts of Ghalghaf and Mazuj are in the ranges of 8-20 and 8-26 mm respectively. The size of the inhibition zone diameter was directly proportional to the concentration of extracts (p< 0. 05). The lowest amount of MIC related to aqueous extract of mazuj gall (0. 128 mg / ml). This study showed that two galls of Mazuj and Ghalghaf are contained of antibacterial compounds that could be used against multi-drug-resistant gram negative bacteria. Therefore the antibacterial activity of other extracts of these galls and pharmacologic studies are necessary.