Evaluation of personal-social developmental skills levels in children with early treated Phenylketonuria
This Study aimed to investigate the level of personal-social developmental skills in children 1-4 years old with early treated phenylketonuria.
This analytic، cross-sectional study has been done on 40 children 1-4 years old referred to clinics of phenylketonuria (PKU) who were diagnosed by screening at birth and were treated. The measurements were a demographic questionnaire، ASQ (Ages & Stages Questionnaire) and clinical assessment by pediatrician. Forty children were also selected randomly as control group from kindergartens of Tehran and completed the questionnaires. Data were analyzed by SPSS 19. 0 software.
The mean age of Children was 30/7 (± 10/5) months in the control group and 27/7 (± 11/0) months in the case group. There was no significant differences between two groups regarding of delivery type and the current and birth، height and weight and head circumference. There was a significant difference between two groups regarding personal-social developmental skills (P <0. 001).
That the level of personal-social developmental skills in the children with early treated Phenylketonuria is lower than normal children. Early diagnosis and intervention for all children with early treated Phenylketonuria is recommended.
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