Evaluation of the Histhomorphological Changes of Intraperitoneal CO2 Pressure Increase on Kidney, Pancreas, Liver and Spleen during Laparoscopic Operations in Dog

During laparoscopy, a working space is established by continuous insufflating aninert gas in the peritoneal cavity whose volume should be large enough to facilitatesurgery without increasing intra-abdominal pressure (IAP) over a threshold limit (usually15 mm Hg). The most commonly used gas is CO2, since it permits safe electrocauteryand is rapidly absorbed and dissolved into blood, thus minimizing the risk of gasembolism. Twenty female mixed breed dogs which chose for an experimental procedurewere prepared. Average of weight was 20 ± 3 kilograms and average recorded of age was 18 ± 1.2 months. They randomly divided to two groups (n10). In control group theintraabdominal pressure was maintained 12 mm/Hg and in test group 20 mm/Hg duringthe operation. Histopathologic evaluations revealed more pathological changes at thekidney of all the dogs in test group (intraabdominal pressure: 20 mm/Hg) in comparisonto control group (intraabdominal pressure: 12 mm/Hg). Findings showed that, the organswith fewer numbers (1 or 2) of arteries and veins are more susceptible to increased intraabdominal pressure.