Myeloid Sarcoma Presenting with Lateral Cervical Mass and Eosinophilia; a Diagnostic and Therapeutic Dilemma: Case Report

Myeloid sarcoma is a rare extramedullary tumor of immature myeloid cells. It has been very rarely reported as lateral cervical mass in English literature. Myeloid sarcoma has also been reported with marked eosinophilia. Here we present a 17 year old boy with lateral cervical mass and persistent eosinophilia. The mass was isointense in MRI and homogenously enhanced after contrast injection which were not specific. Then, microscopic findings revealed blastoid cells with positive reaction for CD68 and CD117 which were highly in favor of myeloid sarcoma rather than its great mimicker, high grade lymphoma.