A Case Report of Sneddon Syndrome

The combination of generalized broken livedoreticularis and cerebrovascular accident is referred to as Sneddon syndrome with the incidence of 4/million/year. It predominates among young women and the more prevalent mean age at the moment of diagnosis is the fifth decade. The disease has a slow and progressive clinical course that can lead to disability or death، due to neurological problems or associated complications. Livedo reticularis is characterized by persistent lesions with a cyanotic coloration، which are not influenced by temperature. Patients should be classified as primary Sneddon syndrome، if no etiologic factor can be detected، and secondary Sneddon syndrome، which occurs mainly as part of an autoimmune disorder or in a thrombophilic state. The severity of the disease seems to be correlated with magnetic resonance imaging aspects، but not to the presence of antiphospholipid antibodies. Histopathological study revealed that the disease affects small and medium arteries، located in the profound dermis and superior band of the subcutaneous cellular tissue. We have reported a patient with recurrent vascular accident who had significant skin lesion named livedoreticularis as long as treating for obsessive convulsive for a long time and infertility. We want to emphasis to see well as the first step of examination for diagnosis and treatment of disease.