Comparison effect of Ketamin-propofol versus alfentanil-propofol for creating analgesia and sedation during cystoscopy

Pain is a complex medical problem creating which inadequate control pain results adverse effects on the patients physiological, metabolic and mental conditions.The aim of this study was comparison effect of Ketamin-propofol with Alfentanil-propofol on creating analgesia and sedation during cystoscopy and comparing the side effects of two drugs and patient and physician satissfaction. In this double- blind clinical trial 140 person who were candidate for cystoscopy were randomly divided into two groups The first group received 1mcg/kg alfentanil with 1mg/kg propofol and the second group received 0.5 mg/kg ketamin with 1mg/kg propofol. Sedation score, pain score, time of cystoscopy and hemodynamic changes determined and data were analyzed by SPSS. The mean of sedation in alfetanil group was significantly more than ketamin group(p=0.001). The mean of pain score in alfetanil group was significantly less than ketamin group(p=0.001). The time of cystoscopy in cystoscopy in alfetanil group was significantly less than ketamin group (p=0.001). Results showed that alfentanil-propofol compare to ketamin-propofol reduced pain score and increased time of sedation with less side effects during cystoscopy. So this study supports the preference alfentanil compare to ketamin.