The prevalence and antimicrobial susceptibility pattern of Shigella species isolated from hospitalized patients, Kermanshah, 2007-2013‎

Shigella species are the most important agent of diarrheal diseases that is known as shigellosis. In this study we investigated the prevalence of shigella species and their antimicrobial susceptibility pattern isolated from hospitalized patients in Kermanshah from 2007 to 2013. In this cross - sectional study demographic data and results of CRP and ESR tests of all hospitalized shigellosis patients were studied. The susceptibility of bacteria was assed using disk diffusion method. The results were analyzed with SPSS 16. Of the total 3977 patients, 129 cases (3.24%) were diagnosed as Shigellosis. The highest rate of infections were seen in under 10 years old patients. The CRP (C-Reactive Protein) test were positive in 79.1% of patients which was meaningful as statistically (p<0.01). Results of antimicrobial susceptibility testing showed that all of isolates were resistant to Cotrimoxazole and tetracycline. The lowest resistant rate of was against cefixime and ciprofloxacin. The results of this study indicated a low prevalence rate of shigellosis and the other hand a high resistance rate of shigella species to some antibiotics. The physicians should pay special attention to prescribe appropriate antibiotics to treatment of this infections in order to reducing of their mortality.