Survey of effect of the listening to Qurane- karim on the sedation and speed of induction in general anesthesia candidates using BIS monitoring

Good preoperative sedation and anxiolysis helps in smooth induction and optimal depth of anesthesia during induction، also laryngoscopy & tracheal intubation will be caused to less hemodynamic perturbation. The objective of this study is determining the effect of listening to holy Quran-e- karim tape before anesthesia on the degree of sedation and speed of induction and also variation of hemodynamic variables during that time. Methods & Materials: In a prospective single blind randomized clinical trial، 60 patients with ASA physical class I & II، candidate for intra abdominal operation under general anesthesia was included. After selection of the patients on the basis of inclusion and exclusion criteria’s، patients divided randomly in two groups (case & control). Before giving any drugs، in the case group 10 min of holy Quran e-karim reading was played via a head phone. But in the second group head phone in the off position was applied. BIS and heart rate was recorded before and after this 10 min in two groups. After that in the same time with premedication injection (Fentanyl & Midazolam) another 3 min record of holy Quran-e Karim was played to group one patients، and again BIS was road. Hence induction of anesthesia was done with thiopental 5mg/ kg and Atracurium 0. 5mg/kg. Time to reaching the BIS number to 50 in two groups was noted. Also BIS and HR recorded at laryngoscopy and after intubation and 2 min later. Data was analyzed with SPSS statistical software version 11. And P-value less than 0. 05 considered valuable. Comparison of initial BIS & HR (after 10 min listening to tape) t-student test showed a meaningful difference between two group (P-value = 0. 05). That means the patients in case group had a better sedation than other group. But analysis of data for other times didn’t show a significant difference between groups. Discussion & Results confirmed that، listening of holy Quran without giving any sedative and analgesic drugs can reduce the BIS number from awareness level to the level of conscious sedation (80