Effects of Caffeine Ingestions Concomitant to Incremental Running Test on Lipid Peroxidation and Enzymatic Antioxidant in Active Men
Abstract:
Purpose
The aim of the current research was to assess effects of caffeine (5 and 9 mg.kg -1) ingestions concomitant to incremental running test on malondialdehyde (MDA) as lipid peroxidation marker and superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) as enzymatic antioxidants.
Material And Methods
Ten subjects were tested on a treadmill until exhaustion on three separate occasions between which there were intervals of 5 days. Every volunteer underwent three conditions containing placebo or caffeine doses that were consumed one hour before exercise (pre-test). Blood samples were collected pre-test, before caffeine or placebo consumption and immediately after exercise (post-test).
Results
Results showed that in comparison to placebo condition, caffeine doses decreased MDA levels and increased GPx activities significantly (P< 0/05). Regardless of 5 mg.kg -1 caffeine ingestion that had no significant effect on CAT and SOD activities (P< 0/05), 9 mg.kg -1 caffeine intake significantly increased and decreased CAT and SOD respectively (P< 0/05), when compared to placebo. For MDA levels, there was no significant difference between caffeine doses (P< 0/05), but these differences for CAT, SOD and GPx were significant (P< 0/05). Discussion and
Conclusion
In conclusion caffeine doses approximately had equal effects on lipid peroxidation decline, while these effects on enzymatic antioxidant with 9 mg.kg -1 caffeine intake were better than 5 mg.kg-1 caffeine.
Language:
English
Published:
Iranian Journal of Health And Physical Activity, Volume:5 Issue: 1, 2014
Page:
9
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