Effect of progressive resistance training on serum A-FABP and Apolipoprotein A-I concentration in male rats

Adipocyte fatty acid-binding protein (A-FABP), a member of FABPs family, plays an essential regulatory role in energy metabolism and inflammation, and apolipoprotein A-1 (apoA1) is the major HDL-associated apolipoprotein. The purpose of this study was to investigate the effect of resistance training with progressive load on serum A-FABP and apoA-I levels. Sixteen male Wister rats (12-14 weeks’ old) were randomly divided into control (n=8) and training (n=8) groups. The training group was subjected to a resistance training program with the use of a ladder (3 days/wk, for 4 wk). Fasting serum levels of FABP and apoA-I concentrations and lipid profile levels in serum and liver were measured. After four weeks resistance training serum FABP and apoA-I levels in training group were significantly higher than control group (respectively, P= 0.026 & P= 0.028). We did not find any significant difference in serum and liver lipid profile between groups. These results indicated that resistance training with suitable intensity could increase serum A-FABP and apoA-I levels.