Assessment of efficacy of prophylactic administration of crystalloid solutions on hemodynamic changes after spinal anesthesia for elective cesarean section

Aim and Now, 95 % of the pregnant experience regional anesthesia. Neuro-axial technique-induced sympathic block may result in hypotension in the mothers and consequently can affect the blood uterus. Different findings regarding the effects of prophylactic hydration prevention of maternal hypotension, the decision to study in this field. The study is a randomized clinical trial, planned in the form of double-blind on 74 pregnant women candidate for the non-urgent cesarean section. They were divided in two groups randomly, the ringer lactate was given to one group (case group; A) while no fluid was given to another one (control group; B) and then procedure of caesarean was done for the two groups under spinal anesthesia. Then, data from the both group that completed the design criteria Apgar first, fifth and tenth in infants, mean arterial blood pressure and heart rate and dose of ephedrine were recorded using statistical tests t-test, ANOVA were analyzed Between mean changes in heart rate, mean arterial pressure, age, Apgar first, fifth and tenth Ringer lactate group and the control group, there was no significant difference between the two groups., but the mean dose of ephedrine (has been given 5mg and the condition of the mother's arterial blood pressure decrease > 20 % of baseline mean arterial blood pressure, mean arterial blood pressure was measured at every turn, ) was less in the case group. Prophylactic fluid therapy before the spinal anesthesia was not efficacious in preventing the hemodynamic changes related to this kind of anesthesia.