Inflammatory Bowel Diseases in Center of Iran,QOM Province, 2007-2011
Message:
Abstract:
Background And Objectives
Inflammatory bowel diseases (IBD) is a chronic immune-mediated intestinal condition, which are divided into two main types of ulcerative colitis (UC) and Crohn's disease (CD). This study was carried out with the aim of determining the epidemiological profile of IBD in Qom province, from 2007 to 2011.
Methods
This descriptive cross-sectional study was performed on 236 patients who were referred with the diagnosis IBD (UC & CD) to gastrointestinal clinics of Qom province from the beginning of 2007 to the end of 2011. The patient's information was collected through face-to-face interview or contacting them. Data analysis was done using descriptive statistical methods, central statistical indices, independent t-, chi-square, exact Fisher, and Mann-Whitney tests at the significance level of less than 0.05.
Results
The mean age for UC was 35.39 years and for CD was 33.03 years. The male to female ratio was 1:1 for UC and 1.28 for CD. The percentage of non-smoker patients in CD and UC was 87.3% and 87.5%, respectively. In patients with UC, the most common complaint was rectal bleeding (64.2%), and in CD patients was abdominal pain (65.6%). In UC patients, the most common involvement of proctitis was 47%, and in CD patients, the most common involvement of terminal Ileum was reported 47%. The mean lag time between the onset of symptoms and definite diagnosis was 13.8 and 20.56 months for UC and CD patients, respectively. In terms of positive family history of IBD, in UC patients, 2.14% were first-degree relatives and 2% second degree relatives, and patients with CD, 3.1% were first-degree relatives and 6.2% second-degree relative.
Conclusion
This study showed a clearer picture of IBD in Qom province, but broader studies are necessary to determine the exact epidemiological status.
Language:
Persian
Published:
Qom University of Medical Sciences Journal, Volume:8 Issue: 3, 2014
Page:
41
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