Effectiveness of safeguard measures in controlling a nosocomial outbreak of Crimean-Congo hemorrhagic fever

Crimean-Congo hemorrhagic fever (CCHF) is a fatal viral infection. Humans become infected through tick bites, contact with infected blood or organs or tissues of human or animals. The disease has caused nosocomial outbreaks with high mortality. Following the admission of a CCHF patient to infectious ward of Imam Reza Hospital in Mashhad a nosocomial outbreak occurred. In 1391, all steps for standard precaution in Health Personnel in the infectious ward of Imam Reza hospital observed for Crimean-Congo hemorrhagic fever. A total of 44 healthcare workers were in contact with the CCHF patients in this study. IgM and IgG antibodies against CCHF virus were studied on their sera, while Crimean-Congo fever antibody titers were negative in all 44 (100%).. There was no serologic evidence of healthcare-related CCHFV transmission in recent outbreak in Imam reza hospital.