Comparing the effects of acute exhaustive exercise on cardiac troponin T serum and malondialdehyde of heart tissue response levels of endurance trained young rats

unlike regular exercise، acute exhaustive exercise may be elicits damage to the heart. The aim of this study was to comparing the effects of acute exhaustive exercise on cardiac troponin T serum and malondialdehyde of heart tissue response levels of endurance trained young rats

48 Wistar male rats were assigned into following three groups (N=16): 1. control (without exercise); 2. experimental (8 weeks exercise + an acute bout of exhaustive exercise); 3. experimental (8 weeks exercise + three acute bout of exhaustive exercise). The end of experimental، half of rats were killed immediately before exhaustive، but the remaining rats were killed immediately after performed an acute bout of exhaustive exercise on the treadmill. malondialdehyde of heart tissue and Cardiac troponin T serum levels were measured by ELISA and TBARS methods، respectively. Data were analyzed by one – way ANOVA

The results show that malondialdehyde of heart tissue group1 (34. 63%)، group2 (31. 09%)، group3 (18. 13%) and Cardiac troponin T serum، group1 (288%)، group2 (162. 5%)، group3 (82. 3%)، were significantly increased following an acute bout of exhaustive exercise compared to before exhaustive. Nevertheless، the increased in group3 was significantly less than other groups (P<0. 05).

Based on the results، it can be concluded that 3 consecutive bout of exhaustive exercise after the 8 weeks exercise compare to singly 8 weeks exercise effectiveness provided protection from myocardial damage induce an acute bout of exhaustive exercise.