Effect of 8 Weeks Aerobic Training on Plasma Apolipoprotein M Levels in Normal and overweight Women

Apolipoprotein M is a new protein located in HDL and has the ability to connect to the cholesterol. There is limited information available regarding the effect of exercise training on circulating levels of apoM. The purpose of this study was to investigate the effect of aerobic exercise on serum apolipoprotein M in normal weight and overweight women. A totallof twenty nine healthy women (31.86 ± 7.04 years) divided in to the two groups based on body mass index: Normalweight (BMI ≤24.9, n =15) and overweight women (BMI ≥25, n =14).The aerobic training program was carried out for 8 weeks, 3 sessions per week at 40-80% of maximal reserved heart rate. Duration of each session was 25 minutes in the first week and it increased up to 45 minutes in the 8th week of exercise. At the beginning and the end of training period, plasma level of apolipoprotein M, HDL, LDL, TG and TC were measured. Fainally 8 weeks of aerobic exercise in normal-weight and overweight women significantly increased the plasma levels of apolipoprotein M, LDL and total cholesterol. while the HDL and TG in both groups showed little change. In addition, after 8 weeks of exercise, there was negatively significant correlation between plasma apolipoprotein M level with, BMI and waisttine to hip ratio in all Subjects. The results of this study suggested that plasma level of apolipoprotein M increase after aerobic exercise training. However, diet control is necessary to determination the exact effect exercise, training on plasma apolipoprotein M levels alterations.