DNA Electrochemical Nanobiosensors for the Detection of Biological Agents
Author(s):
Abstract:
In this study, we explained a nanobiosensor for DNA sequence detection, featuring sequence specificity, cost efficiency, speed, and ease of use. Without the need for labels or indicators, it may be ideal for the detection of biological agents. This review describes recent advances in electrochemical impedance spectroscopy (EIS) with an emphasis on using nanoparticles and nanotechnology. A powerful biosensor system requires a high-performance biosensor component as well l as a user-friendly instrumental setup. However, biosensor setups have to be adapted to specific applications. Rapid, selective and sensitive detection technologies for biological agents are critical in clinical diagnosis, environmental monitoring and food safety. Recent developments in nanomaterial create many opportunities to advance DNA sensing and gene detection. The fact that gold nanoparticles are able to provide a stable immobilization of biomolecules that retain their bioactivity is a major advantage for the preparation of biosensors. Although, there are a lot of researches reporting electrode modification by different nanomaterial to improve the DNA biosensor performance, the preparation of nanomaterial or the electrode modification strategy is often relatively complex. Furthermore, some DNA biosensors based on nanomaterial modification are still very limited for the improvement of DNA biosensor performance. Thus, the construction of nanostructure modified electrode by a simple strategy to improve the DNA detection sensitivity is highly desirable.
Language:
English
Published:
Journal of Applied Biotechnology Reports, Volume:2 Issue: 1, Winter 2015
Pages:
175 to 185
magiran.com/p1392245
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!