Effects of cell phone waves on granular cells migration of cerebellum in neonatal rat

Increasing use of mobile phones is caused an increase of concerns about biological effects of cell phone waves (CPWs) on the body tissues, especially on the central nervous system. The aim of this study was to investigate the effect of CPWs on migration of cerebellum granular cells in neonatal rat. In this experimental study, 40 neonatal rats were randomly divided in 4 groups (n=10), one control group and three case-groups (I, II, III). In the days 7-13 of post-born, the case-groups I, II, and III were irradiated to the CPWs from 10cm for 0.5, 2, and 8 hrs; respectively. After killing the rats in day 14, tissue sections were prepared and the granular cells of the internal layer of the cerebellum were counted using Motic software. Furthermore, thickness of the external granular layer was measured using Nikon software. Comparing group III to control-group, the cell numbers of internal granular were decreased significantly (P<0.05). Moreover, in group III, the ratio of the cerebellum-weight to the body-weight decreased significantly (P<0.05) as well as the external layer thickness decreased significantly compared to control group (P<0.05). CPWs with increasing migration of granular cells leads to anatomic changes. Finally, it prevents from cerebellum development and can lead to disorder in its metabolic activities.