Comparing the lung functional tests and high-resolution computed tomography scan's results in systemic sclerosis
Message:
Abstract:
Introduction
The main outcome of systemic scleroderma is progression to pulmonary complications. Early diagnosis is important in treatment and management of patients with lung involvement. In this study we compared lung functional tests and high-resolution computed tomography scan’s results with each others، in order to find a reliable non-invasive modality instead of biopsy for detection of lung involvement in patients with systemic sclerosis.
Materials And Methods
In this descriptive cross-sectional study، from 2012 to 2014، patients with systemic sclerosis that hospitalized in Imam Reza hospital in Mashhad were enrolled. Pulmonary function tests and high-resolution computed tomography scans were performed at the same time. Data were analysed by SPSS16.
Results
Overall 12 males (mean age: 35±10 years) and 31 females (mean age: 41± 16 years) were studied، 3 patients left the study. High-resolution computed tomography scan’s findings were abnormal in 32 patients (80%) and the most feature of lung involvement was ground glass pattern in 46. 9 %. We found significant correlation between disease duration and high-resolution computed tomography scan (r=0. 03، p=0. 04).
Conclusion
these findings illustrate the potential role of high-resolution computed tomography scan in early detection of pulmonary involvement as a non-invasive modality for lung screening in patients with scleroderma. Acknowledgment: This study was supported by Rheumatic Diseases Research Center and Mashhad University of Medical Sciences، further more there was not any conflict of interest in doing this research.
Language:
Persian
Published:
Medical Journal of Mashhad University of Medical Sciences, Volume:58 Issue: 2, 2015
Pages:
65 to 68
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