The Effect of Long-Term Garlic Supplementation with Two Different Doses on Protein Damage after an Exhaustive Exercise

The aim of this study was to investigate the effect of long-term garlic supplementation with two doses of 500 and 1000 mg on protein damage after an exhaustive exercise in non-athlete students. 26 male non-athletes (mean age 21±1.23 yr, weight 69.38±8.28 kg and height 178.9±6.11 cm) were divided randomly into three groups: the placebo group (n=8) and two garlic supplementation groups (n1=9 and n2=9) with two dosages of 500 and 1000 mg/day. The first and second blood samples were collected at the baseline and after the exhaustive exercise and the third and fourth samples were taken after 8 weeks of supplementation in the baseline and after the exhaustive exercise. The data were analyzed by ANOVA with repeated measures and one-way ANOVA (α=0.05). The results showed that a session of exhaustive exercise significantly increased protein damage. In addition, long-term garlic supplementation with 500 and 1000 mg/day decreased protein damage in the baseline and after the exhaustive exercise. Also, 1000 mg of garlic consumption decreased protein damage more than 500 mg supplementation in the baseline and after the exhaustive exercise. Therefore, athletes are recommended to consume long-term garlic supplementation in order to prevent oxidative stress caused by intensive exercises.