The effect of acute endurance exercise on plasma myoststin in healthy elderly men

The aim of this study was to investigate the effect of acute endurance exercise on amount of Myostatin, as most important protein that involved in sarcopenia, in healthy elderly men 11 healthy elderly men (age= 68±2.1 years, height= 177±1.3 cm, weight= 79±1.5) volunteered for participation in this study. At the first, the subject’s descriptive and physiological measurements have been done. 72hours after the determination of maximal oxygen consumption (VO2max), subjects performed acute endurance exercise via 70% VO2max. 3 blood samples were collected from Antecubital vein at before, immediately and 4hours after the exercise, for investigation of effect of endurance exercise on plasma Myostatin. Plasma Myostatin was measured by ELISA method. One-way ANOVA used for statical analyses. Significant level was set at P≤0.05. The results of this study showed that at immediately and 4hours after the exercise the plasma Myostatin decreased, 45.47% (P=0.002) and 53.53% (P=0.001) respectively. These decrements were significant. Also, plasma Myostatin at 4ours after the exercise decreased non-significantly (15.87%) compared to immediately after the exercise. The results of this study revealed that plasma Myostatin decreased significantly in the response to endurance exercise, in healthy elderly men. Presumably, according to the results of this study prescription of endurance exercise may could decreases Myostatin and subsequently sarcopenia in elderly people.