Study Clinical Symptoms and Para-Clinical Findings in Poisoning Patient with Aluminum Phosphide in Patients Referred to Imam Khomeini Hospital in Ardabil (Northwest of Iran)

Aluminum phosphide is used in different area in Iran. According to that the herbal form of these pills are used increasingly, comparison and evaluation of these patients in terms of clinical and laboratory symptoms are important. We studied on clinical and Para-clinical findings in patients who had taken aluminum phosphide and its herbal form in this study. This is a descriptive and analytic study which carried out during 2006-2012. In this study, laboratory variables, white blood cell count, hematocrit, blood glucose, sodium, potassium and bicarbonate, arterial blood gas also clinical finding after taking aluminum phosphide pills, and vital signs of poisoned patients were extracted. In this study 386 poisoned patients were evaluated. We divided poisoned patients in two groups, case and herbal. 35% had been taking original Aluminum phosphide (case group) and 65% herbal form (herbal group). In totally 18.7% of poisoned patients were male. The average age of patients in herbal group was 23.22 ±8.20 years and in case group was 24.78±7.04 years. In both groups, nausea and vomiting were the most prevalent clinical signs. Experiments in a separate group showed significant different in blood pressure upper (P<0.001), Po2 level lower (P<0.001), pH lower (P<0.001) and bicarbonate lower (P<0.001) but there was no significant difference in respiratory rate, temperature, hemoglobin level and hematocrit. Also was observed that 70.4% of patients in case group died but all patients in herbal group survived (P<0.001). The results of this study indicated that arterial blood gas of patients is a useful tool for differentiating oral poisoning with original and herbal rice pill. Hence, in patients with clinical toxicity of rice tablet can be used to differentiate these two tablets.