Treating a Patient with Bone Marrow Edema Syndrome with Iloprost

Bone Marrow Edema Syndrome (BMES) is an uncommon، self-limited and with unknown etiology characterized by severe pain with no history of trauma. Due to low prevalence of BMES and its non-specific signs، correct diagnosis is often delayed intensifying bone pain and impairing patients’ function and quality of life. In this study we treated a patient with bone marrow edema syndrome in right ankle with Iloprost successfully that suffered pain in this region almost 4 months and NSAID، physiotherapy and steroid treatments was not benefited.