Study of Maternal risk factors associated with the incidence of congenital heart disease: a Case-Control study

Congenital heart defects are called to a situation which comes from birth and effects on the baby''s heart and its performance، different types of these defects can range from mild (like a small hole between the heart chambers) to rigid (such as a flaw or weakness in a part of the heart). This is a case-control study. All newborn which their echocardiogram screening test at birth was abnormal during the years 2011 and 2012 were participated in the study as cases. For the control group، all the children who were not diagnosed with any disorders were participated in the study and were matched according to sex and living area. Statistical methods such as descriptive statistical analysis، t student، and logistic regression modeling was performed using SPSS 16 for analyzing data. All tests were done with significance level of 0. 05. After logistic regression modeling، it was determined that history of stillbirth in pregnant women (OR=7. 85)، not taking a multivitamin before pregnancy (OR=4. 38)، maternal obesity during pregnancy (OR=3. 02)، and maternal weight gain during pregnancy (OR=2. 09) were risk factors that had orderly the highest correlation with this disorders. It seems that factors such as a history of stillbirth in pregnant women، mothers taking multivitamins and obesity can have a significant impact in the development of congenital malformations of the heart in infants.