The effect of 12 weeks resistance exercise on plasma levels of Apelin-12, Nesfatin-1 and resting heart rate in hypertensive elderly women

Adipokine including Apelin and Nesfatin secreted by adipose tissue and. The aim of present study was to investigate the effect of 12 weeks resistance exercise on plasma plasma levels of Apelin-12، Nesfatin-1 and resting heart rate in hypertensive elderly women In this study، 30 hypertensive elderly women were chosen and randomly divided in to two groups: Control and Resistance exercises group (training، 3 times a week for 12 weeks). Blood pressure، heart rate; and also plasma Apelin and Nesfatin concenterations were measured before and at the end of study. Data evaluated by using the dependent and independent t-test significant level data p≤ 0. 05 was done. That was found after 12 weeks of Resistance exercise significant differences in serum levels Apelin (reduce، p=0. 02) and Resting heart rate (reduce، p=0. 03) in the experimental group was occurs but in the control group،no significant changes in serum levels Apelin (p=0. 50) and Resting heart rate (p=0. 12) was occurs. Also، after 12 weeks of Resistance exercise no significant differences in serum levels Nesfatin (p=0. 15) in the experimental group was occurs but in the control group، significant changes in serum levels Nesfatin (increase، p=0. 05) was occurs. The 12-week resistance exercise، could reduction resting heart rate and blood pressure And thus eliminates the need to increase Apelin and decrease Apelin observed (negative feedback). The study did not exercise as an effective incentive to reduce Nesfatin.