Anaphylactic shock after use of bovine Pasteurella vaccine in East Azerbaijan dairy herd

Anaphylactic shock in farm animals after use of some drugs and biologic reagents is usual. In September of 2013, Pasteurella vaccines were injected to in 1200 non-pregnant cows and calves that were older than 3 months. Thirty minutes to 12 hours after vaccination, confusion, collapse, hypoxia, hypotension, orbital edema, tachypenea, tachycardia and cyanotic mucous membranes were seen. Furthermore, in some cases, the sign of sweating, nausea, dyspnea and profuse sweating discharge of eye, mouth and nose were seen and 3 cows were died. Emphysema, edema and lung congestion were seen at necropsy. A significant increase in the number of RBC and neutropenia was observed. According to the history, clinical and laboratory findings and necropsy, anaphylactic shock caused by vaccine side was detected.