Normal calcium, sodium and potassium to creatinine ratio in Babol healthy adolescents

Due to difficulty of obtaining a 24h urine (especially in children), a random urine calcium sample is recommended to detect of hypercalciuria. However, recent studies have shown that the urinary calcium/creatinine ratio varies with age and geographic areas. So, the aim of this study was determining the normal value of urinary calcium to creatinine ratio in healthy adolescent’s children. Four hundred eight children of 12 to 14-year-old were randomly selected from middle school in Babol (north of Iran) and early morning urinary samples of them were studied for determining normal urine Ca/Cr, Na/Cr and K/Cr ratios. Children who had the family with the history of renal disease were excluded from this study. In this study the 50% and 95% of urinary Ca/Cr ratio were 0.08±0.02 and 0.13 mg/mg for the whole group. The mean of urinary Ca/Cr ratio in boys and girls were 0.08±0.03 and 0.08±0.02, respectively. The mean of urinary Na/Cr ratio in boys was 1.4±0.48 and in girls was 1.21±0.33. Also, the mean of urinary K/Cr ratio in boys and girls were 0.30±0.11 and 0.29±0.10, respectively. This study was shown that the urinary Ca/Cr ratio of these children is different from other geographic areas. Also, a direct relationship was seen between urinary Ca/Cr ratio, Na/Cr and k/Cr ratios.