Evaluation of organisms causing infectious endocarditis in children during 10 years

Infective endocarditis is a disorder with high mortality and morbidity in children specially in whom with Congenital Heart Disease(CHD) .The target of our study is a description of the factors affecting pediatric Infective endocarditis particularly in whom with CHD in Mashhad.
this cross-sectional study includes 19 patients less than 18 years old with endocarditis hospitalized in the Department of Pediatric Cardiology( University of Mashhad Medical Sciences) between 1381 to1391.Clinical symptoms, risk factors, underlying heart disease ,laboratory- echocardiogeraphic results were studied. Finally data were analyzed by using SPSS 16 software.
Endocarditis were seen in 21.1% of children with previous underlying infectious disease. According to results of blood cultures Staphylococcus aurous was the most common crime ( 21%).Each of Coagulase-negative staphylococci, Staphylococcus epidermidis and gram-negative cocci were seen in just one patient.10.6% of children had Umbilical /vein catheter history. The most common underlying factor was congenital heart disease (47.7%). Having history of surgery in 7(36.8%) patients due to CHD before endocarditis were detected .Vegetation were resected in 2 (10.5%)children as a treatment after endocarditis .There was no significant difference between time of surgery and microbial crime(p-value= 0.069). Cardiac vegetation was seen in 18 children(94.7%).One child (5.2%) died.
According to irrecoverable effects of infectious endocarditis in children, it seems that strong clinical suspicion also considering of underlying causes and negative results of blood cultures , especially in children with congenital heart disease can be crucial in reducing mortality and complications of infectious endocarditis.