Histopathological comparison of the effects of Ceylon cinnamon, Plantagolanceolata and Flaxseed linum on experimental cutaneous wound healing process in rats

Wound healing is an important process that requires specific factors and conditions. Various medications have been developed to accelerate wound healing, among them; herbal medicines are the safest and more effective of them. The present study was performed to verify the effects of Ceylon cinnamon, Plantagolanceolata and Flaxseed linum on cutaneous wound healing in rats.
Ninety-Six rats were divided into twelve groups of eight. Wounds were induced on the skin area around the vertebral column. Herbal pre-prepared ointments with different concentrations were administered on the wound area.
The results showed that cinnamon extract accelerated the wound healing process and specifically increased epithelialization. The later effect was more effective than that of Plantagolanceolata and Flaxseed linum. Also the Plantagolanceolata wound closure effect was significantly faster than the Flaxseed linum. Histopathological evaluation of the wound healing in the day fourteenth after the treatment showed that the highest rate of wound healing was observed with Ceylon cinnamon and that Plantagolanceolata and Flaxseed linum were the next in rank.
Generally, comparative evaluation of these therapeutic plants suggests that Plantagolanceolata extract produce the best healing effect on cutaneous wound healing process than the other comparable medicinal plants.