The Effect of Six Weeks Aerobic Training on Fibrinogen and Some of the Coagulation Factors in Women with Type 2 Diabetes

More than 80% of diabetic subjects die because of cardiovascular complications. The main symptom of this disease is thrombosis which occurs due to the increase of coagulation factors and imbalance in the homeostasis. The aim of present study was to investigate the effect of six weeks aerobic training on fibrinogen and some of the coagulation factors in women with type 2 diabetes.
Subjects and Among women with type 2 diabetes, 20 patients were chosen. They were randomly divided in two groups: experimental (n=12; age:47.41±6.59 yr, BMI: 28.79±3.92) and control (n=8; age:48±5.9 yr, BMI:30.87± 2.18). The experimental group performed the training for 6 weeks, each week 4 sessions with 50–80 % heart rate reserve. Blood samples were taken 24 h before the first training session and 48 h after the last training session. Covariance test was used to evaluate the data and in order to compare each group’s pretest and posttest, paired-samples T-test was used at the significance level of P ≤0.05.
There were significant increase in fibrinogen (P= 0.007), PTT (P=0.001), PT( 0.001) and significant decrease in platelet (P= 0.001) of the experimental group.
Present study indicated that 6 weeks aerobic exercise caused changes in coagulation factors which is beneficial to deal with threatening complications coagulation system in patient with type 2 diabetes.