Poisoning of dog by tebuconazole fungicide-a case report

This case report surveys a six years old male dog which was perished in 2 hours. The clinical symptoms including depression, anorexia, diarrhea, severe thirst and foamy saliva was seen. Albeit the supportive treatment, the dog was perished. Formalin-fixed samples of liver and kidney were collected for pathological examination. Besides, for toxicological experiments the frozen gastric contents along with part of liver, heart, kidney, brain, spleen and blood experiments were sent to Toxicology Research Center of Veterinary Medicine School of Tehran University. Necropsy findings revealed the congested, dark and dehydrated organs. Histopathological studies showed bleeding, congestion and necrosis in kidney and liver tissues along with fatty changes in hepatocytes. According to the pinkish appearance of gastric contents, existence of carcass (possibly a crow) and wheat seeds imbedded with pink color, we speculated that the dog was probably poisoned by a fungicide. In toxicological examinations using gas chromatography method (GC-NPD), the cause of poisoning was revealed to be tebuconazole fungicide. This is the first report of tebuconazole intoxication in dogs in Iran.