Antibacterial Effects of EthanolExtract of Plantago psyllium on Antibiotic-Resistant Salmonella typhimurium

Plantago psyllium isone of the most widely used medicinal plants in Northern Europe¡ North Africa and South Asia.Salmonella typhimuriumis a gram-negative opportunistic pathogen and the common causes of digestive tract infections.The aim of this study was to evaluate the effect of Plantago psyllium on Salmonella typhimurium;due to increasing drug resistance.
Plantago psylliumwas collected from Sistan and Baluchistan provinceVacuum device (rotary)was usedfor extraction of maceration mwthod. Strains of Salmonella typhimuriumwere isolated from poultry in Zabol. The MIC and MBC for Plantago psylliumextract was determined in different concentrations by dilution method in the wells on bacteria andSusceptibility to ampicillin and penicillin antibiotics was evaluated by Kirby-Bauer disk diffusion method.
The results showed that maximum MIC for psyllium extract on Salmonella typhimurium was 10 mg/ml and ten strains was inhibited in this concentration and in the one strain of Salmonella typhimuriumno growth was observed; while minimum MIC for the pathogen was 5mg/ml and only one strain was inhibited in this concentration. The highest Minimum Bactericidal Concentration (MBC) against Salmonella typhimurium was 20 mg/ml in ten strains; while the lowest MBC was 10mg/ml in one strain.
It was found thatantimicrobial effect of psyllium extract on Salmonella typhimurium is high and similar research in this field could be done to find alternatives for synthetic compounds.