Combined Factor V and Factor VIII Deficiency: A Case Report

Combined factor V and factor VIII deficiency (F5F8D, OMIM 227300) is a rare autosomal recessive bleeding disorder. It seems more common among Jews and Iranians, particularly in regions with frequent consanguineous marriages.
Case Report: We describe a 5-yearold girl born out of consanguineous marriage with a complaint of prolonged bleeding after dental extraction. There were no history of spontaneous bleeding and other coagulation defect symptoms.
In frequent consanguineous marriage regions, inherited deficiency of factor V and VIII should be considered in patients with coagulation defect symptoms.