Sero-prevalence of Hepatitis B Infection in Patients with Intellectual Disability - Ali Akbar Boarding House Center- Southern khorasan- 2014

Hepatitis B virus (HBV) infection is an important worldwide public health problem and it has been cause of elevated morbidity and mortality rates. The prevalence of HBV among patients with mental disturbances is higher than normal population. Living in institutes, comparing home, leads to higher probability of hepatitis. This study was conducted to determine HBV markers among patients with intellectual disability.
Material and This study of 220 patients with intellectual disability living in Ali Akbar boarding house center. Socio demographic data were obtained from questioners and blood sample were taken and tested to determine HBS Ag, HBS Ab, anti HBC-total. The results was analyzed with SPSS-15.
Of the 220 patients, 36.4% female and 63.6% were male. The mean age was 33.5±13.3 years eight affected with Down syndrome, 198 with intellectual disability and 14 affected with other mental disturbances. 24% had aggressive and biting behavior. HBS Ag was positive in 3.2%.35.5% and 79.1% was Anti- HBC and Anti- HBS positive, respectively. It is not significant difference between HBS Ag, Anti- HBC prevalence and duration of stay in center. (P=0.23), (P=1)
Prevalence HBS Ag positive in downs syndrome was higher than other mental patients but there is no significant difference HBS Ag prevalence and kind of mental disability.
HBS prevalence in male was 69.3% and being this difference statistically significant (p=0.001). Also, Anti-HBS prevalence in intellectual disability patients were higher than other patients and being this difference statistically significant. (0.02)
The results of present study show high HBV sero prevalence in patients with intellectual disability. According to high risk behavior and transmission of HBV in mental retardation centers importance of HBV specific prevention measures in this groups of patients are emphasized.