Relationship between Serum Levels of C-reactive Protein and Ssymptoms of Acute Appendicitis in Patients with Acute Appendicitis

Appendicitis is the most common and the most important medical emergency and most of these patients undergo appendectomy. The diagnosis of appendicitis is critical and value of diagnostic laboratory tests has always been discussed. The purpose of this study was to determine the diagnostic value of increasing of CRP in the diagnosis of acute appendicitis.
This was a cross- sectional study. 105 persons of recourse to Shahid Motahari hospital emergency of Marvdasht in 2012, were examined. Before giving any preoperational Antibiotics, blood samples for measurement of serum CRP levels were prepared. After surgery, the relationship between serum levels of CRP and appendix tissue biopsy and the surgeon about the type of tissue to be investigated. All data were analyzed by SPSS version 18 (ANOVA and Tukey test).
81 patients of participants that were studied had acute appendicitis and 24 of them had normal appendix. Among patients with acute appendicitis, 65 patients had increased serum CRP levels and 16 patients had normal serum CRP levels. The sensitivity and specificity of CRP respectively were 80% and 63% in this study.
The results showed that evaluation of serum CRP levels can be useful and beneficial in the diagnosis of acute appendicitis.