Prevalence and Risk Factors of Hepatitis B Infection in Pregnant Women of Iran: A Systematic Review and Meta-Analysis
Abstract:
Introduction
Identification of prevalence and risk factors of hepatitis B (HBV) in pregnant women is very important as a major source of infection in HBV prevention program. Therefore, this review study was performed with aim to determine the prevalence and risk factors of hepatitis B (HBV) infection in pregnant women of Iran.
Methods
Current study was conducted based on PRISMA checklist for systematic review and meta-analysis studies. To access to the English and Persian documents, two independent authors searched Scopus, PubMed, ScienceDirect, Cochrane, Web of Science (ISI), Springer, Online Library Wiley, Magiran, Iranmedex, SID, Medlib, IranDoc and also Google Scholar search engine without any time limitation to January 2016 by using mesh keywords including: Prevalence, Hepatitis, Pregnant women, Pregnancy, Risk Factors, Hepatitis B Surface Antigens, HBsAg, and HBeAg. Data was analyzed using the fixed-effects model via Stata software (Version 11.1).
Results
A total of 36 eligible studies with sample size of 64,193 pregnant women in Iran, HBV prevalence was estimated 0.5%. Minimum and maximum of this range were related to the North (0.4%) and East (1.6%) of the Iran. HBV prevalence in urban and rural pregnant women was estimated 1.1 and 1.2%, respectively. The prevalence of HBeAg, HBeAb, HBsAb in pregnant women of Iran were calculated 0.05, 0.05 and 40%, respectively. Among the risk factors, illiteracy, abortion, history of blood transfusion and husband addiction were significant related with prevalence of HBV (P0.05).
Conclusion
The lowest prevalence of HBV in Iran was related to pregnant women and less than the general population. History of blood transfusions, husband addiction, illiteracy and abortion are associated with HBV in Iranian pregnant women.
Language:
Persian
Published:
Iranina Journal of Obstetrics Gynecology and Infertility, Volume:19 Issue: 200, 2016
Pages:
16 to 29
magiran.com/p1571162  
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