Effect of Spirulina platensis on Testicular Tissue Structure and Sex Hormones in Male Mice

Author(s):
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Abstract:
Inroduction &
Objective
Spirulina platensis is a blue-green algae that has antioxidant and antiinflammatory compounds. In this study the effects of Spirulina platensis on spermatogenesis in male mice was investigated.
Methods
40 mice were randomly divided into 4 groups(n=10), Control: normal saline, Experimental 1: 75 mg/kg, experimental 2: 150 mg/kg and experimental 3: 300 mg/kg of Spirulina platensis received via gavage(During treatment= 30 days, every other day). After treatment the right testis of mice removed and fixed. The tissue stained with H&E. In tissues lineage cells of spermatids , epithelial thickness measured. Levels of testosterone , FSH and LH checked out. Data were analyzed with ANOVA and Duncan test. Level significant was p
Results
The number of spermatogonia , spermatocytes , epithelial thickness and level of testosterone, FSH and LH in experimental 3 increased significant compared with control group .
Conclusion
Spirulina platensis consumption in male mice increase the number of spermatids , FSH and testosterone.
Language:
Persian
Published:
Journal of Plasma and Biomarkers, Volume:9 Issue: 3, 2016
Page:
21
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