Effect of isoflurane with different dose on bleeding and hemodynamic changesin patiants under going endoscopic sinus surgery

Endoscopic sinus surgery is0T5T 0T5Tthe0T5T 0T5Tmost0T5T 0T5Tcommon0T5T 0T5Tactions in the field of ear, nose and throat that such acts always accompanied with bleeding that can cause hemodynamic disorders and direct effect on the outcome of the surgeon.0T5T 0T5TThe use of anesthesia drugs can help to control hemodynamic ,isoflurane can help keep blood pressure in the ideal range.The aim of this study was to evaluate the hemodynamic with different percentages of isoflurane in endoscopic sinus surgery was done.
Methods and reviews: In a clinical trial, 90 patients were randomized to 3 groups of 30 people,0T5T 0T5TASA0T5T 0T5Tclass I and II were selected.0T5T 0T5TThe induction was the same in both groups, the first group following the induction of isoflurane0T5T 0T5Twith0T5T 0T5T1 percent and 1.2 percent in Group 2 and Group 30T5T 0T5T1.5 Badrsd was used.0T5T 0T5TFixed-dose group and remifentanil0T5T 0T5Tg /0T5T 0T5Tkg / min μ0.1were used during surgery.
The demographic characteristics and the duration of operation were not significant in the three groups (P> 0.05). mean arterial pressure in 15,30,45,60 min after start of surgery reduced significantly between group 1&3,group 2&3 and also heart rate in 30,45 min after start of surgery had significantly reduction change between group 1&2.
Isoflurane 1.5 percent compared to 1.2 percent and 1 percent 5Tsignificant5T the arterial blood pressure and heart rate are generally affected at different times.The average heart rate in Group 2 with 1.2 percent lower than other groups.