The Effects of Jujube Fruit (Ziziphus vulgaris) Powder in Antioxidant Capacity Elevation and Prevent of Inflammation Detection Due to Diabetes in Wistar Rat
Abstract:
Introduction
Diabetes is a metabolic and chronic disorder. One of the safe treatments in diabetes disease is the use of herbal plants in traditional medicine. The aim of this study was to consider the antioxidant and anti-inflammation effectof ziziphus vulgaris (jujube) in contrast with diabetes.
Materials and Methods
In this study, 30 Wistar rats were studied in three groups including control diabetic, non control diabetic and treatment group for 5 weeks. The animals intreatment group were treated with the powder of jujube (1 g/kg bw) for two weeks. After two weeks, stereptozotocin (60 mg/kg bw) was used for induced diabetes in animal except non diabetic control group. Afterwards, the animals were treated for three weeks in the same way. At the end of the study the animal blood samples were taken and the antioxidant content of serum, malondialdehyde (MDA) and C-reactive protein (CRP) were measured. Data analysis was done by statistical tests as: Kruskalwallis and Wilcoxon singed ranks.
Findings: The content of MDA and CRP had a significant decrease in comparison with diabetic control group in animals that received the powder of jujube before induction of the diabetes (P>0/05). In the end of study, the content of serum antioxidant in the rats that treated with jujube showed a significant increase in comparison with diabetic rats too (P>0/05).
Discussion &
Conclusions
The jujube fruit has antioxidant and anti-inflammatory action and it is useful in preventing inflammation due to diabetes and diabetes treatment.
Language:
Persian
Published:
Ilam University of Medical Science, Volume:24 Issue: 5, 2017
Pages:
55 to 64
magiran.com/p1634215  
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 990,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
دسترسی سراسری کاربران دانشگاه پیام نور!
اعضای هیئت علمی و دانشجویان دانشگاه پیام نور در سراسر کشور، در صورت ثبت نام با ایمیل دانشگاهی، تا پایان فروردین ماه 1403 به مقالات سایت دسترسی خواهند داشت!
In order to view content subscription is required

Personal subscription
Subscribe magiran.com for 50 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!