Evaluation of clove (Syzygium aromaticum) essential oil on the oxidation indice and bioaccumulation of lead following oral administration of lead in the Japanese Quail

Some heavy metals are toxic at low concentrations and can create free radicals that damage the cell. Essential oils have antioxidant properties and can chelate some toxic elements And prevent of bioaccumulation of these elements .
TBARS assay and ICP-OES have used for evaluating of oxidative stress and measurement of bioaccumulation of lead in liver and muscle of quail, respectively. All measurements were carried out in triplicate and data were analyzed using SPSS 20.0 for Windows.
The results of this research in 21 and 35 days showed that mean concentration of MDA in liver and muscle of lead group was higher than others and this difference was significant. The measurement of lead in liver and muscle in 21 day were not detected by ICP-OES. In 35 days the bioaccumulation of lead in liver and muscle (µg/g) was higher than other groups and this difference was significant.
The results showed that the clove essential oil is effective in reducing of malondialdehyde concentrations (mg / kg) and reduces the bioaccumulation of lead in liver and muscles of quail.