Bilateral Choroidal Detachment Induced by Unilateral Topical Brinzolamide Timolol Maleate Fixed Combination

We describe a 66-year-old man who developed bilateral choroidal detachment that was induced by unilaterally administered topical fixed brinzolamide 1%– timolol maleate 0.5% combination early after an uneventful phacoemulsification surgery which we believe was an idiosyncratic reaction most likely against the brinzolamide. The condition improved rapidly after the cessation of fixed combination with only topical prednisolone acetate every hour and 1% cyclopentolate BİD bilaterally. Though, there were several similar cases with choroidal detachment in the literature associated with oral acetazolamide and topical dorzolamide; the present case is the first case with bilateral choroidal detachment observed after brinzolamide administration.