The Prevalence of iroN gene in Escherichia coli strains isolated from UTI patients in Hamedan city

Aim and One of the most genes in exacerbation UTI is iroN gene. The purpose was determination of iroN gene prevalence in E. coli strains. To accomplish this goal can a reasonable mechanism to manage the inhibition of bacteria carrying the gene and preparation of vaccine offered.
A total of 80 samples from patients with UTI symptoms collected and Fifty E. coli isolates, identified. E. coli presence has been confirmed by biochemical and microbial tests. PCR was done by specific primers. The apmplicon size was 668 bp.
Among the 50 isolated bacteria from UTIs, 9 isolates carried out iroN gene. This was equivalent 18% of total isolates. Gene prevalence in women was twice the prevalence in men. One and two urban areas had the highest prevalence of the gene.
The prevalence of iroN gene was relatively high. There are numerous reports of the presence of antibodies aginst iroN protein in patient's serum which is emphasis on the presence of antigenic determinant. It can be used in the preparation of a vaccine against UTI bacterial infections Produced by E. coli. Our results can also be used by epidemiologists and health care providers.