Study of relationship between serum vitamin D level and IgE in allergic children

In recent years, the role of vitamin D deficiency in the incidence and aggravation of types of allergy have been considered and much study has been done in this regard. Because vitamin D deficiency and as well as the prevalence of allergy is the important issues in the health field, this study was aimed to investigate the relationship between vitamin D level and and IgE in children in Tehran.
In a cross sectional study, 112 allergic children aged less than 12 years (64 boys and 48 girls) were evaluated. Vitamin D was classified in three levels as deficient ( The mean of vitamin D level was 64.17±27.14ng/ml that fall into insufficient range. The abnormal level of vitamin D was present in 61.9% (20.5% insufficient and 41.4% deficient). Vitamin D deficiency was significantly higher in girls(P=0.03). Although vitamin D deficiency was increased with age, the mean of vitamin D deficiency was not different between age groups. However, 43.8% of total IgE levels were higher than normal range, there was no association between serum vitamin D and IgE level.
Given the prevalence of vitamin D deficiency in the children and its impact on the incidence of allergic diseases, design a national project to determinate the vitamin D deficiency levels and its associated risk factors, and screening of vitamin D deficiency seems necessary.