Compare adequate intraoperative fluid therapy with Ondansetron on the incidence and severity of nausea and vomiting after general surgery

Message:
Abstract:
Background
One of the most common and unpleasant side effects of surgery and anesthesia are nausea and vomiting, which causes spasms, aspiration and demand for drugs. The researchers suggest several drugs and methods to be able to reduce its complications.
Objective
Compare adequate intraoperative fluid therapy with Ondansetron on the incidence and severity of nausea and vomiting after general surgery
Methods
In this double blind clinical trial, 120 patients undergoing general surgery participated. Patients were randomly divided into 3 groups. Group 1- adequate intraoperative fluid therapy-, Group two- pharmacological intervention with Ondansetron 0.06 mg per kg of body weight - and group three - without prophylactic intervention-. the severity and incidence of nausea and vomiting evaluating Based on self-reporting scale in three stages - After surgery , 2 and 6 hours after surgery -. the data were analyzed with Spss software.
Results
The results showed that the three groups were similar in terms of intervening variables.. According one-way ANOVA, severity and incidence of nausea and vomiting were significantly different among the three groups in the recovery phase.
Conclusion
Adequate fluid therapy can reduce the incidence of nausea and vomiting after surgery.
Language:
Persian
Published:
Iranian Journal Of Anaesthesiology and Critical Care, Volume:38 Issue: 3, 2016
Pages:
59 to 69
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