Compare adequate intraoperative fluid therapy with dexamethasone on the incidence and severity of nausea and vomiting after general surgery
Message:
Abstract:
Background
nausea and vomiting are one of the most common and unpleasant side effects of surgery and anesthesia, which causes spasms, aspiration, need more medicine. The researchers said several drugs and methods to reduce any adverse affects caused it.
Methods
In this double blind clinical trial, 120 patients undergoing general participated. Patients were randomly divided into 3 groups. Group 1- adequate intraoperative fluid therapy-, Group two- pharmacological intervention with dexamethasone 0.1 mg per kg of body weight along with induction of anesthesia- and group three - without prophylactic intervention-. Based on self-reporting scale, the severity and incidence of nausea and vomiting evaluating in three stages- After surgery , 2 and 6 hours after surgery -. the data were analyzed with Spss software.
Results
Result showed that the three groups are homogeneous in terms of confounding variables. According one-way ANOVA, the difference between severity and incidence of nausea and vomiting was significantly different among the three groups in the recovery phase, So that based on post hoc test the difference between the control and fluid therapy with dexamethasone group was significant, And both dexamethasone and fluid therapy are not significant differences in terms of these variables together.
Conclusion
Adequate fluid therapy can reduce the incidence of nausea and vomiting after surgery
Language:
Persian
Published:
Armaghane-danesh, Volume:21 Issue: 10, 2017
Pages:
950 to 963
magiran.com/p1668878  
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